||The aim- to examine the operating room nurses‘ professional competence. Methodology. The survey has been conducted from September 2014 until January 2015 in tertiary health care institution using the questionnaire - Nurse competence scale. The survey involved 103 operating room nurses working in the Abdominal Surgery‘s, Heart Surgery‘s, Urology‘s, Cardiac arrhythmias and Radiology‘s, Ear, Nose and Throat Diseases, Eye diseases, Obstetrics and Genecology’s, Plastic and Reconstructive surgery‘s departments. The results. The professional level of the operating room nurses’ competence was very high (80,05 points), university-educated operating room nurses assessed their education better. In practice the operation room nurses most usually used the elements of the professional competence‘s categories of critical situations’ management, the other elements of the professional competence‘s categories were the elements of the role of work, the role of assistance, the elements of the therapeutic interventions’ and diagnostic functions’ categories. Best the operation room nurses assessed the professional competence‘s elements of the critical situations‘ management category, according to assessment, the other elements of the professional competence‘s categories were the elements of the role‘s of work, of the therapeutic interventions‘, of the role‘s of assistance, diagnostic functions‘ and quality assurance‘s categories. Conclusions. Particular attention in the operation rooms must be paid to the quality assurance, training, the following categories of the competence elements were named by the operation room nurses as most rarely used. The operation room nurses have worst assimilated the training / coaching category’s elements.